Sahar Poudineh; Alireza Sarlak; Shima Mohamadian; Siamak Najafi; Esmaeil Behzadi; Maryam Poudineh
Abstract
Background: Infertility causes social and psychological distress and has negative economic effects on healthcare systems. Infertility is the incapability to conceive after at least 12 months of unprotected regular sexual intercourse. Finding the impacts of herbal antioxidants can result in new visions ...
Read More
Background: Infertility causes social and psychological distress and has negative economic effects on healthcare systems. Infertility is the incapability to conceive after at least 12 months of unprotected regular sexual intercourse. Finding the impacts of herbal antioxidants can result in new visions for enhancing male fertility. Quercetin belongs to the bioflavonoids family, and many nutritionists, scientists, and researchers have investigated its pharmacokinetic and pharmacodynamic properties in their studies.Methods: In this review, the authors summarized the protecting role of quercetin against oxidative damage and toxic metals stimulating male infertility by searching in PubMed, Web of Science, Scopus, and Embase via the keywords “male infertility”, “quercetin”, “male fertility”, “oxidative stress”, “toxic metals”, “environmental contaminants”, and “heavy metals” without language or date restrictions.Results: Due to insufficient antioxidant defenses and inadequate cell repair systems, spermatozoa are predominantly susceptible to oxidative stress and toxic agents, especially heavy metals. Reactive oxygen species mediate several other cellular mechanisms, such as apoptosis. Previous research has highlighted quercetin and polyphenols’ positive and negative impact on male fertility.Conclusion: Quercetin exerts its beneficial functions through its antioxidant capacity by scavenging ROS and chelating toxic heavy metals and other environmental contaminants; thus, it can prevent male infertility.
Soudabeh Sabetian; Bahia Namavar Jahromi; Farnia Feiz; Isabella Castiglioni; Claudia Cava; Sina Vakili
Abstract
Background: The coronavirus disease-2019 (COVID-19), caused by a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is now spread worldwide. Therefore, informative and reliable data related to the exact effects of COVID-19 on fertility and pregnancy is still of great interest until the ...
Read More
Background: The coronavirus disease-2019 (COVID-19), caused by a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is now spread worldwide. Therefore, informative and reliable data related to the exact effects of COVID-19 on fertility and pregnancy is still of great interest until the pandemic is declared over. General guidelines regarding the protection and management of COVID-19 have been published and new information will continue to be updated daily.
Methods: In this review, we summarized clinical health guidelines for reproductive and infertility centers to improve quality management in assisted reproductive technology and minimize the potentially harmful consequences of COVID-19 on pregnancy and fertility.
Results: As specified in the literature, protocols consist of five categories, including protocols for couples, protocols for women, protocols for men, labor and delivery, and postpartum and breastfeeding.
Conclusion: General protocols for patients and staff may vary depending on specific conditions. However, this review provides some rules to ensure their safety against the disease during the pandemic.
