Alireza Mirahmadizadeh; Mousa Ghelichi-Ghojogh; Fatemeh Rezaei; Mehdi Nejat; Haleh Ghaem; Jafar Hassanzadeh; Mohammadreza Karimi; Zohre Khodamoradi; Kimia Jokari; Leila Jahangiry
Abstract
Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can be transmitted through direct, indirect, or close contact with infected people by contaminated respiratory droplets or saliva. This study aimed to investigate the epidemiology of coronavirus disease 2019 (COVID-19) and the secondary ...
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Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can be transmitted through direct, indirect, or close contact with infected people by contaminated respiratory droplets or saliva. This study aimed to investigate the epidemiology of coronavirus disease 2019 (COVID-19) and the secondary attack rate (SAR) in the cases’ close contact.Methods: A total of 431 confirmed COVID-19 patients were randomly selected using systematic random sampling from 15 May to 13 June 2020. The required data were extracted from the CORONALAB database of the Center for Disease Control and Prevention (CDC) at Shiraz University of Medical Sciences. Detection of COVID-19 was performed using Real- Time Polymerase Chain Reaction (RT-PCR) and nasopharyngeal swabs. SAR was also calculated for different groups.Results: Among the index cases, 64.27% were male, 24.80% were public sector employees, and 4.87% were admitted to the intensive care unit. In addition, most of them aged 30-39 years. The SAR was 11.56% (95% CI: 9.86% to 13.25%) in the close contacts. Accordingly, the highest SAR was observed among the friends, 19.05% (95% CI: 7.17% to 30.92%), followed by the spouses of COVID-19 cases, 16.67% (95% CI: 10.81% to 22.51%). Furthermore, diabetes (6.03%) and cardiovascular disease (5.1%) were the most common comorbidities among the index cases.Conclusion: The findings suggested that the SAR was relatively lower among the close contacts. Considering the familial and non-familial relationships between the index cases and their close contacts were the major causes of disease transmission. Therefore, it is crucial to conduct tracing for COVID-19 contacts in all cases with whom patients have had close contact.
Mohammad-Rafi Bazrafshan; Ahmadreza Eidi; Zahra Keshtkaran; Nasrin Shokrpour; Parisa Zand; Hamed Delam
Abstract
Background: In December 2019, a series of pneumonia cases of unknown cause appeared in Wuhan, China, which was very similar to viral pneumonia. In late January 2020, the World Health Organization named this disease the sixth public health emergency of international concern due to an increase in ...
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Background: In December 2019, a series of pneumonia cases of unknown cause appeared in Wuhan, China, which was very similar to viral pneumonia. In late January 2020, the World Health Organization named this disease the sixth public health emergency of international concern due to an increase in the number of COVD-19 cases. This study was designed to determine different epidemiological and clinical aspects of COVID-19 worldwide. Methods: This is a review study. We searched for articles related to COVID-19 from December 20, 2019 to June 05, 2020. Two researchers performed the search separately, and finally articles containing information on coronavirus, its mortality and epidemiology and clinical characteristics of the patients were selected for review and extraction. Results: The results of various studies show that the most common symptoms of the disease include fever, cough and fatigue, and the most common respiratory symptom is Rhinorrhoea. Transmission occurs primarily when an infected person sneezes or coughs through respiratory droplets, such as the spread of influenza and other respiratory pathogens. Some studies have reported that the COVID-19 incubation period is an average of 4.6 days, ranging from 1.2 to 11.1 days and can potentially be asymptomatic. Conclusion: The significant increases in the morbidity and mortality necessitate prevention and control activities by educating people on important health issues such as staying at home, using clean masks and gloves, as well as performing proper and timely medical interventions.