Maryam Nejabat; Mohammadreza Heydari; Parisa Keshani; Hassan Joulaei; Nazanin Nazari
Abstract
Background: There are some debates about the possible unintended effects of genetically modified (GM) crops on consumer health. The gut microbiota plays an important role in maintaining the health of the host, especially in gastrointestinal diseases. The current review focuses on the studies with the ...
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Background: There are some debates about the possible unintended effects of genetically modified (GM) crops on consumer health. The gut microbiota plays an important role in maintaining the health of the host, especially in gastrointestinal diseases. The current review focuses on the studies with the aim of evaluating whether their outcomes indicate any adverse effects of feeding genetically modified (GM) crops on alteration and the count of gut microbiota.Methods: A structured literature search was performed independently by three authors on Scopus, Web of Science, PubMed, and Embase on the 1st of July 2019. In total, 333 publications were obtained by the search strategy, which decreased to 306 after excluding the duplicates. Furthermore, experimental studies that have designed a control group and were written in English were included in the review. After reviewing the full texts, 16 studies were included. To access the quality of articles, we used the Cochrane checklist.Results: Ten publications (62.5%) used 50% or more genetically modified (GM) diet in the treatment group. In 11 studies (68.7%), the duration of animal feeding was 90 days or more. There were no significant differences in the experimental and control groups of both male and female rats on the 90th day; it can be concluded that non-genetically modified (GM) and genetically modified (GM) rice diets did not cause any changes in the gut bacteria. Data analysis of different animal models showed that the most changes in the microbial flora were observed in the chicken and the least in the rat. In the studies in this review, all microbial isolates were anaerobic, and the Lactobacillus and Enterococcus families were common organisms.Conclusion: Based on our literature review, we claim that there is not any significant difference in gut microbiota between the control group and the group with a transgenic diet. The mechanisms of the effects of genetically modified (GM) foods on the gut microbiota in animals should be explicated in future studies. Nevertheless, this study provides valuable information for research on genetically modified (GM) foods and whether they are useful or detrimental to human health.
Hassan Jolaei; Mostafa Abdollahi; Maryam Safarirad; Enayat Berizi; Mohammad Hashem Yousefi; Seyyed Mohammad Ali Noori
Abstract
Background: Improper use of antibiotics and not paying attention to withdrawal time causes antibiotics to enter the milk, which can cause allergies in humans and cause antibiotic-resistant pathogenic bacteria in the long run, so quality and hygienic milk control is essential.Methods: This study aimed ...
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Background: Improper use of antibiotics and not paying attention to withdrawal time causes antibiotics to enter the milk, which can cause allergies in humans and cause antibiotic-resistant pathogenic bacteria in the long run, so quality and hygienic milk control is essential.Methods: This study aimed to investigate the prevalence of antibiotic residues in milk as a systematic review and metaanalysis from 2004 to 2021 for 15 years in Iran. The data were collected from four international search databases, including PubMed, Scopus, Science Direct, and Google Scholar, and four Iranian databases, including SID, MagIran, Civilica, and IranDoc.Results: After reviews of 314 studies, 38 were finally selected, and the information was recorded and analyzed in Stata software. The results of this study show that the residual prevalence of antibiotics in milk using the screening method was 28% (CI: 0.34-0.22). The residual rates of antibiotics using enzymelinked immunosorbent assay (ELISA) and high-pressure liquid chromatography (HPLC) methods were 43% (CI: 0.26-0.59) and 27% (CI: 0.05-0.49), respectively.Conclusion: The data obtained from the meta-analysis show that despite various reports of a quantitative amount of antibiotic residue in milk, the average amount in the ELISA method was 16.98 ppm. Although the prevalence of antibiotics in Iran is relatively high, a quantitative amount is optimal. Also, since the use of antibiotics in livestock is almost inevitable, proper withdrawal time of antibiotics can play an important role in preventing the release of antibiotic residues in milk.
Fariba Moradi; Zohreh Balaghi; Hassan Joulaei; Najaf Zare; Samad Mohammadi; Mohsen Moghadami
Volume 2, Issue 4 , October 2014, , Pages 140-144
Abstract
Background: Prevention of unwanted pregnancy is a key strategy to improve the women’s health through spacing of birth and avoiding pregnancy at high-risk maternal ages. Unmet need by definition is the percentage of fecund married women who are not using contraceptives while they do not want to get ...
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Background: Prevention of unwanted pregnancy is a key strategy to improve the women’s health through spacing of birth and avoiding pregnancy at high-risk maternal ages. Unmet need by definition is the percentage of fecund married women who are not using contraceptives while they do not want to get pregnant. They do this due to unavailable quality services, limited choice of methods, lack of information, safety concerns or side-effects and partner disapproval. The present study aimed to assess the magnitude of unmet need for prevention of unwanted pregnancy in Shiraz.Methods: In this descriptive cross-sectional study, 2000 married women of childbearing age (10-49 years) were selected randomly in a survey in Shiraz. Data collection was done using a researcher-made questionnaire and the results were reported using descriptive statistical methods.Results: In the present study, 85.6% of the women used a contraceptive method. 58.7% of them used modern methods of contraception. Reported reasons for not using contraceptives included recent delivery (25%), intention to have more children (20.6%), lack of awareness about contraceptive methods or where such services were offered (6.3%) and irregular sexual intercourse with husband (4.5%). Interrupted intercourse ranked the highest among the methods used. Finally, the unmet need for prevention of unwanted pregnancy in this study was reported to be 4.3 percent.Conclusion: Women in Shiraz had a relatively lower level of unmet need. Counseling is recommended for higher risk women with unmet need in order to keep the descending trend of unmet need for prevention of unwanted pregnancy in Shiraz.
Fariba Moradi; Hassan Joulaei; Masuomeh Saffari; Najaf Zare; Mohammad Hossein Fallah Zadeh
Volume 1, Issue 1 , July 2013, , Pages 14-18
Abstract
Background: The purpose of this study was to determine the prevalence of depression symptoms and the effect of various demographic characteristics on its severity in an elderly population in Fars province, southern Iran. Methods: This cross-sectional study was conducted during May and September 2009. ...
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Background: The purpose of this study was to determine the prevalence of depression symptoms and the effect of various demographic characteristics on its severity in an elderly population in Fars province, southern Iran. Methods: This cross-sectional study was conducted during May and September 2009. A sample of 1461 men and women, aged more than 60 years were selected using a multistage stratified random sampling method. Levels of depression symptoms were measured using the Geriatric Depression Scale (GDS). Data were analyzed using SPSS software. Also, analysis of variance (ANOVA) and correlation analysis were performed to find the correlation between the variables and GDS score. Results: Overall, 1443 people completed the questionnaire. The prevalence of the symptoms mild to moderate depression (GDS: 5-10) was 51.1%, while that of severe depression symptoms (GDS >10) was 19.7%. There were significant relationships between sex, marital status, educational level, occupation, residential place and the GDS scores. Conclusion: The prevalence of depression symptoms was high among the elderly in Fars Province. Therefore, if properly trained, primary care teams could help these patients.
