Hassan Jolaei; Mostafa Abdollahi; Maryam Safarirad; Enayat Berizi; Mohammad Hashem Yousefi; Seyyed Mohammad Ali Noori
Abstract
Background: Improper use of antibiotics and not paying attention to withdrawal time causes antibiotics to enter the milk, which can cause allergies in humans and cause antibiotic-resistant pathogenic bacteria in the long run, so quality and hygienic milk control is essential.Methods: This study aimed ...
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Background: Improper use of antibiotics and not paying attention to withdrawal time causes antibiotics to enter the milk, which can cause allergies in humans and cause antibiotic-resistant pathogenic bacteria in the long run, so quality and hygienic milk control is essential.Methods: This study aimed to investigate the prevalence of antibiotic residues in milk as a systematic review and metaanalysis from 2004 to 2021 for 15 years in Iran. The data were collected from four international search databases, including PubMed, Scopus, Science Direct, and Google Scholar, and four Iranian databases, including SID, MagIran, Civilica, and IranDoc.Results: After reviews of 314 studies, 38 were finally selected, and the information was recorded and analyzed in Stata software. The results of this study show that the residual prevalence of antibiotics in milk using the screening method was 28% (CI: 0.34-0.22). The residual rates of antibiotics using enzymelinked immunosorbent assay (ELISA) and high-pressure liquid chromatography (HPLC) methods were 43% (CI: 0.26-0.59) and 27% (CI: 0.05-0.49), respectively.Conclusion: The data obtained from the meta-analysis show that despite various reports of a quantitative amount of antibiotic residue in milk, the average amount in the ELISA method was 16.98 ppm. Although the prevalence of antibiotics in Iran is relatively high, a quantitative amount is optimal. Also, since the use of antibiotics in livestock is almost inevitable, proper withdrawal time of antibiotics can play an important role in preventing the release of antibiotic residues in milk.
Alireza Mollaei; Maryam Hamidian Shirazi; Amir Reza Hamidian Shirazi
Abstract
Background: The presence of antibiotic residues in milk and other livestock by products is a health hazard that can endanger the public health. Antibiotics are widely used in animal husbandry to treat bacterial infections. In this industry, antimicrobial drugs are being used for decades; as a result, ...
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Background: The presence of antibiotic residues in milk and other livestock by products is a health hazard that can endanger the public health. Antibiotics are widely used in animal husbandry to treat bacterial infections. In this industry, antimicrobial drugs are being used for decades; as a result, continuous administration of antibiotics to livestock had led to contamination of industrialized dairy farms. Background: This research was conducted to evaluate antibiotic residues in raw milk samples in Sepidan, using ECLIPS 50 kit and TWINE SENSOR kit. Methods: In this cross-sectional study, one hundred raw cow milk samples were randomly collected from different farms and milk factories in Sepidan and Beyza townships from winter 2017 to spring 2018. The ECLIPS 50 and TWINE SENSOR kits were used to monitor antibiotic residues in milk samples. The data were analyzed employing Chi-square test, using SPSS software version 20. The significance level was considered p <0.05. Results: In total, 100 raw milk samples were collected, of which 60 (60%) were from Beyza and 40 (40%) from Sepidan. A total of 95 samples (95%) were antibiotic-free and 5 (5%) contained antibiotic residual. 5 samples (5%) of ECLIPS 50 kit, 5 samples (5%) of TWINE SENSOR kit were shown to be positive, using both kits. Conclusion: There was no difference between ECLIPS 50 kit and TWINE SENSOR kits in detecting antibiotics residue in raw milk samples. The positive samples in the two sets of kits were identical. Furthermore, there was no significant difference between the two types of kits
Shiva Faghih; Mehdi Hedayati
Volume 3, Issue 2 , April 2015, , Pages 50-55
Abstract
Background: Although it is assumed that calcium has beneficial effects on weight loss, the interaction of calcium and iron would be a major concern. We did this study to investigate the effects of calcium and low-fat milk on serum ferritin in overweight or obese premenopausal women. Methods: Sixty-four ...
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Background: Although it is assumed that calcium has beneficial effects on weight loss, the interaction of calcium and iron would be a major concern. We did this study to investigate the effects of calcium and low-fat milk on serum ferritin in overweight or obese premenopausal women. Methods: Sixty-four healthy overweight or obese premenopausal women recruited in Shahid Beheshti University of Medical Sciences clinics participated in this clinical trial. Participants were randomly allocated to one of the following dietary regimens for 8 weeks: 1) a control diet providing a 500 kcal/day deficit, with 500-600mg/day dietary calcium; 2) a calcium- supplemented diet identical to the control diet with 800mg/day calcium carbonate 3) a milk diet providing a 500kcal/day deficit and containing three servings of low fat milk. Serum ferritin and anthropometric indices were measured at baseline and after 8 weeks. Primary outcome measure was serum ferritin level. Results: Mean±SD of baseline values for age, body mass index (BMI), waist circumference (WC), and serum ferritin were 37.44±9.46 (year), 30.79±3.63 (kg/m2), 88.04±8.90 (cm), and 59.20±47.8 (μg/l), respectively. There were no significant differences in baseline age, BMI, WC, and serum ferritin among 3 groups. Mean values of serum ferritin reductions were 0.26±20.36, 14.59±17.07 and6.57±25.93 (μg/l) in control, calcium, and milk groups, respectively. Reduction in serum ferritin was only significant in the calcium group (P=0.003). Serum ferritin reductions were not significantly different among the 3 groups (P=0.260). Conclusion: An energy-restricted diet in combination with calcium supplement or low-fat milk does not induce any additional adverse effect on iron status, compared to an energyrestricted diet alone.
Shiva Faghih; Alireza Abadi; Mehdi Hedayati; Seyed Masoud Kimiagar
Volume 2, Issue 3 , July 2014, , Pages 88-92
Abstract
Background: Obesity and metabolic syndrome are serious public health problems. It is suggested that high calcium diet can improve lipid profile, blood pressure and insulin resistance.Methods: In this clinical trial, 75 healthy overweight or obese premenopausal women were randomly allocated to one of ...
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Background: Obesity and metabolic syndrome are serious public health problems. It is suggested that high calcium diet can improve lipid profile, blood pressure and insulin resistance.Methods: In this clinical trial, 75 healthy overweight or obese premenopausal women were randomly allocated to one of the following dietary regimens for 8 weeks: 1) a control diet 2) a calcium-supplemented diet containing 800mg/d calcium carbonate 3) a high milk diet containing three servings of low fat milk (all of them providing a 500kcal/day deficit). At baseline and after 8 weeks, waist circumference (WC), blood pressure, serum triglyceride (TG), fasting blood sugar (FBS), and high density lipoprotein cholesterol (HDL-C) were measured.Results: After 8 weeks, WC, FBS and HDL-C decreased in all groups (P<0.001), but there were no significant reduction in TG and blood pressure. Reduction of WC in the milk group was significantly higher than the controls (P=0.028). Also, reduction of HDL-C in the calcium and milk groups was less than the controls (P=0.023 and P=0.019, respectively). Changes in FBS, TG and blood pressure were not significantly different among the 3 groups.Conclusion: We found that increasing milk consumption led to more WC reduction. Milk or calcium intake caused less adverse effect on HDL-C, but has no effect on the blood pressure, FBS and TG. So increase in milk or calcium intake can reduce WC among the metabolic syndrome complications.