Elahe Shamshirgardi; Fatemeh Najafitirehshabankareh; Neda Haghighat; Nitin Shivappa; James R. Hebert; Maedeh Jabbari; Yalda Mortazavi; Laya Saeid; Zahra Shamekhi
Abstract
Background : Inflammation, a risk factor for cardiovascular disease (CVD), is affected by diet.Dietary inflammatory index (DII) is used to determine inflammation of diet. In addition, Neck circumference (NC), an indicator for upper-body subcutaneous adipose tissue distribution, is related to cardiovascular ...
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Background : Inflammation, a risk factor for cardiovascular disease (CVD), is affected by diet.Dietary inflammatory index (DII) is used to determine inflammation of diet. In addition, Neck circumference (NC), an indicator for upper-body subcutaneous adipose tissue distribution, is related to cardiovascular risk factors. This study aimed to examine the correlation between DII and NC in a nationally representative sample case and control.
Methods: In this cross-sectional study, the case group was chronic heart disease patients hospitalized in Al-Zahra Heart Clinic, Shiraz, Iran (N = 100). The Control group did not suffer from any heart-related diseases. Dietary intake data were determined using a single interview and food frequency questionnaire (FFQ). NC was assessed using standard methods. Nutritionist-4 software was used to analyze nutrient intakes from FFQ. The method of Shivappa et al. was used to calculate DII.
Results: The mean of NC in the case and control group were 39.09±4.18 and 36.68±4.32 cm. The mean of DII in the case and control groups were -0.018±1.53 and 0.40±155. There was no significant difference between the DII score of the case and control groups (p:0.056, t:-1.922). No significant correlation was observed between DII score and NC in the case(p:0.750,r:0.032) and control(p:0.294,r:0.106) groups.
Conclusion: There was no correlation between DII score as a risk factor for CVD and NC in both case and control groups.
Mohammad Hassan Eftekhari; Maryam Ranjbar Zahedani; Atefeh Kohansal
Abstract
Background: Normal Body Mass Index (BMI) = 18.5-24.9 kg/m2 and high Body Fat (BF), have been defined as Normal Weigh Obesity (NWO), which can increase the risk of Metabolic Syndrome (MetS) and cardiovascular diseases. The present study aimed to determine the association between NWO and MetS indicators, ...
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Background: Normal Body Mass Index (BMI) = 18.5-24.9 kg/m2 and high Body Fat (BF), have been defined as Normal Weigh Obesity (NWO), which can increase the risk of Metabolic Syndrome (MetS) and cardiovascular diseases. The present study aimed to determine the association between NWO and MetS indicators, Insulin Resistance (IR), and inflammatory and oxidative stress indices in NW obese compared to normal weight women referring to Imam Reza medical center, Shiraz, Iran. Methods: In this case-control study, 41 healthy NW obese Iranian women were recruited and compared to 45 healthy non-obese control subjects. Anthropometric features, body composition, blood pressure, inflammation and oxidative stress indices, fasting insulin, lipid profile, and blood sugar were measured. IR was also assessed by means of special formulas. Results: The results showed a significant difference between the NWO and the control group regarding anthropometric measurements and body composition, including waist (p=0.008) and hip (p<0.001) circumferences, BF (p<0.001), skeletal muscle (p=0.03), protein(p=0.04), body cell mass(p=0.02), bone mass content(p=0.04), and arm circumference(p<0.001). All subjects had normal systolic and diastolic blood pressures. However, the NWO group showed significantly higher serum concentrations of triglycerides (p=0.02), total cholesterol(p=0.02), and C-reactive protein (p<0.001). On the other hand, the results of McAuley test indicated significantly lower insulin sensitivity in the NWO group (p=0.03). Besides, serum MDA concentration did not have a marked differences in both study groups. Conclusion:
Hossein Safari; Mohammad Hassan Eftekhari; Jafar Hassan Zadeh; Arash Dashtabi
Volume 5, Issue 2 , April 2017, , Pages 59-65
Abstract
Background:Serum vitamin D (VIT D) concentration has been inversely associated with the prevalence of metabolic syndrome (MS), but the relationship has remained unclear. We evaluated the prevalence of VIT D deficiency, and its association with MS, and its components in the adult population in a sunny ...
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Background:Serum vitamin D (VIT D) concentration has been inversely associated with the prevalence of metabolic syndrome (MS), but the relationship has remained unclear. We evaluated the prevalence of VIT D deficiency, and its association with MS, and its components in the adult population in a sunny tropical region (Lamerd: a city in the south of Iran)Patients and Methods: Totally, 210 patients referring to different medical centers across the Lamerd city participated in this cross-sectional study through January and February of 2016. To select medical service center, we used a one-stage cluster sampling method. Anthropometric indices and dietary intake were measured using modified food frequency questionnaire (FFQ) and blood samples collected. Data were analyzed using SPPS version 16, Pearson’s correlation was used to investigate the bivariate relationships between the variables, and unpaired t-test was used to determine the differences between genders for all variables. A P-value < 0.05 was considered statistically significant.Results:Overall, 62 menand 144 womenwith a mean age of 35.84± 10.84 years old completed this study; the prevalence of VIT D deficiency among the participants equaled 64.1% (women=66.7% and men=58.1%). A significant positive relationship between sun exposure time on the serum VIT (p= <0.0015), and a negative relationship between the serum VIT D on triglyceride (p= 0.035), TC (p= 0.025, age (p= 0.001), and fasting blood sugar (p= <0.001) were found.Conclusions: This study showed that lower VIT D concentrations were associated with increased MS risk factors.
Masoumeh Akhlaghi; Majid Kamali; Farideh Dastsouz
Volume 4, Issue 4 , October 2016, , Pages 181-188
Abstract
AbstractBackground: Vitamin D deficiency is implicated in a wide rangeof pathological situations including cardiovascular diseases.This study aimed to investigate the association between serum25-hydroxy vitamin D (25(OH)D) and risk factors of metabolicsyndrome and cardiovascular diseases.Methods: The ...
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AbstractBackground: Vitamin D deficiency is implicated in a wide rangeof pathological situations including cardiovascular diseases.This study aimed to investigate the association between serum25-hydroxy vitamin D (25(OH)D) and risk factors of metabolicsyndrome and cardiovascular diseases.Methods: The cross-sectional study was conducted on 169adults (88 males, 81 females) aged 19-52 years living in Shiraz,Iran. Anthropometric characteristics and blood pressure weremeasured using standard methods. Blood samples were collectedin fasting state for determination of blood glucose, lipids, and25(OH)D. Data were analyzed with one-way analysis of varianceand linear regression using SPSS software.Results: Serum 25(OH)D concentrations were considerablyhigher in males. One third of females had vitamin D deficiency(25(OH)D <10 ng/ml) while one third of males exhibited25(OH)D levels >50 ng/ml. In males, systolic and diastolicblood pressure, triglycerides, and metabolic syndrome scoreincreased and high-density lipoprotein (HDL) cholesteroldecreased across tertiles of serum 25(OH)D. On the contrary,in females body mass index (BMI) and metabolic syndromescore decreased and HDL cholesterol increased across tertilesof 25(OH)D. Linear regression, after controlling for confoundingfactors, showed that diastolic blood pressure (B=0.07; 95% CI:0.02, 0.11; P=0.006), triglycerides (B=0.54; 95% CI: 0.22, 0.85;P=0.001), and metabolic syndrome score (B=0.01; 95% CI: 0.001,0.01; P=0.02) positively and HDL cholesterol (B=-0.05; 95% CI:-0.09, -0.01; P=0.02) inversely associated with tertiles of 25(OH)D concentrations in males. In contrast, BMI (B=-0.06; 95% CI:-0.11, -0.02; P=0.01), waist circumference (B= -0.12; 95% CI:-0.23, -0.01; p=0.04), and metabolic syndrome score (B=-0.02;95% CI:-0.03, -0.01; P=0.01) were inversely and HDL-C (B=0.16;95% CI: 0.02, 0.31; P=0.02) positively associated with 25(OH)D tertiles in females.Conclusion: The results suggest that both low and uppernormal levels of 25(OH)D are associated with increased risk ofcardiovascular diseases and metabolic syndrome.
Shiva Faghih; Alireza Abadi; Mehdi Hedayati; Seyed Masoud Kimiagar
Volume 2, Issue 3 , July 2014, , Pages 88-92
Abstract
Background: Obesity and metabolic syndrome are serious public health problems. It is suggested that high calcium diet can improve lipid profile, blood pressure and insulin resistance.Methods: In this clinical trial, 75 healthy overweight or obese premenopausal women were randomly allocated to one of ...
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Background: Obesity and metabolic syndrome are serious public health problems. It is suggested that high calcium diet can improve lipid profile, blood pressure and insulin resistance.Methods: In this clinical trial, 75 healthy overweight or obese premenopausal women were randomly allocated to one of the following dietary regimens for 8 weeks: 1) a control diet 2) a calcium-supplemented diet containing 800mg/d calcium carbonate 3) a high milk diet containing three servings of low fat milk (all of them providing a 500kcal/day deficit). At baseline and after 8 weeks, waist circumference (WC), blood pressure, serum triglyceride (TG), fasting blood sugar (FBS), and high density lipoprotein cholesterol (HDL-C) were measured.Results: After 8 weeks, WC, FBS and HDL-C decreased in all groups (P<0.001), but there were no significant reduction in TG and blood pressure. Reduction of WC in the milk group was significantly higher than the controls (P=0.028). Also, reduction of HDL-C in the calcium and milk groups was less than the controls (P=0.023 and P=0.019, respectively). Changes in FBS, TG and blood pressure were not significantly different among the 3 groups.Conclusion: We found that increasing milk consumption led to more WC reduction. Milk or calcium intake caused less adverse effect on HDL-C, but has no effect on the blood pressure, FBS and TG. So increase in milk or calcium intake can reduce WC among the metabolic syndrome complications.