Jwan Jellal Rasheed Shwana; Burhan Tahir Saeed; Fattah Hama Rahim Fattah
Abstract
Background: Androgenetic alopecia (AGA) is a common form of hair loss that significantly affects individuals’ self-esteem,psychological well-being, and quality of life. This study aimed to investigate the prevalence, epidemiology, pathophysiology, and clinical implications of AGA among adults in ...
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Background: Androgenetic alopecia (AGA) is a common form of hair loss that significantly affects individuals’ self-esteem,psychological well-being, and quality of life. This study aimed to investigate the prevalence, epidemiology, pathophysiology, and clinical implications of AGA among adults in Sulaimani Governorate, Iraq.Methods: A cross-sectional study was conducted in Sulaimani Governorate from September 2022 to December 2023. A stratified sampling method was used to select 1,438 participants aged 18 years and older. Data were collected through a researcherdesigned questionnaire and clinical examinations using the Ludwig and Norwood-Hamilton scales. Descriptive statistics, logistic regression, and Pearson’s chi-square test were used fordata analysis.Results: The study population consisted of 49.7% males (n=715) and 50.3% females (n=723), with mean ages of 32.23±10.04 and 31.46±11.19 years, respectively. Females exhibited a higher incidence of sudden hair loss (27.5%) compared to males (18.3%). Significant risk factors included a family history of hair loss (OR=1.29, 95% CI: 1.23–1.35, P=0.001) and recent general operations (OR=1.07, 95% CI: 1.01–1.15, P=0.023). Additionally, the use of flat irons/curling irons (OR=1.09, 95% CI: 1.10–1.18, P=0.001) and frequent use (>3 times/week) (OR=1.04, 95% CI: 1.02–1.35, P=0.002) were associated with increased hair loss.Conclusion: This study provides important insights into the epidemiology and risk factors of AGA in Sulaimani Governorate, Iraq. The findings underscore the need for targeted prevention and treatment strategies that consider the distinct characteristics of the local population. Further research is warranted to investigate the genetic and environmental factors that contribute to AGA in this region.
Ratnakar Shukla; Nidhi Shah; Sharmila Patil; Anant Patel; Mohammad Goldust; Ruchita Hasija; Nitin Nadkarni
Abstract
Background: This study was performed to describe clinical profile of patients with androgenic alopecia and investigate the efficacy of autologous platelet-rich plasma (PRP) injection in androgenic alopecia.Methods: In this prospective study, adult patients in stage III-VI androgenic alopecia were enrolled. ...
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Background: This study was performed to describe clinical profile of patients with androgenic alopecia and investigate the efficacy of autologous platelet-rich plasma (PRP) injection in androgenic alopecia.Methods: In this prospective study, adult patients in stage III-VI androgenic alopecia were enrolled. Their clinical profile, i.e., age, duration of alopecia, history of previous treatment, family history of alopecia, pattern of alopecia, grade of alopecia, and hair pull test were noted. The enrolled patients were treated with PRP once a month for 3 months and evaluated with clinical photographs. Hair density and hair thickness were measured using USB portable digital trichoscope and digital computerized trichoscan analysis. Clinical evaluation was performed using a 4-point scale including worsening, no improvement, mild improvement, and moderate to significant improvement. Patients were followed every month for 4 months after the procedure.Results: Out of 36 patients, 7 (20%) had a history of previous treatment and 12 (33.3%) had a positive family history of alopecia. The mean (SD) hair count of 17.33 (4.42) at visit 1 increased to 19.20 (6.24) at visit 4 (P<0.0001). The mean hair thickness increased from 0.07 (0.058) mm at visit 1 to 0.11±0.09 mm at visit 4 (P<0.0001). Overall, clinically significant and mild improvement was observed in 11 (33.66%) and 9 (30%) patients, respectively. No improvement was observed in 4 (13.33%) patients, whereas 2 (6.66%) patients experienced worsening of the condition.Conclusion: PRP is effective in increasing the hair count and hair thickness. However, clinically significant improvement was observed in only one third of the patients. PRP can be considered as an adjuvant treatment for patients with androgenic alopecia.
