Document Type : Original Articles


1 Department of Occupational Health, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran;

2 Department of Radiology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran


Background: Noise is one of the most important hazardous physical factors in industrial environments. This study aimed to determine the effects of noise exposure on serum cortisol level and some blood parameters among male workers of a steel production company.Methods: This cross-sectional study was conducted on 50 male workers in a steel production company. In order to assess the changes in blood parameters, such as serum cortisol level, lipid profile, and blood sugar, blood samples were taken from the participants before and after the work shift. Besides, CEL 440 sound level meter was used to measure the equivalent sound pressure level (LAeq) and analyze the noise in octave band frequencies. Analyses of data were performed by SPSS software (version 16) using the Paired sample t-test.Results: The laboratory findings indicated an increase in serum cortisol at all exposure levels. However, the changes were not statistically significant. An increase was observed in blood sugar levels at all the three noise levels and the increment was statistically significant at 95 dB noise level.Conclusion: The present study showed that exposure to high sound levels leads to changes in biological parameters, although under the scenario explained in this study these changes did not reach statistical significant.


  1. Mead NM. Noise Pollution: The Sound behind Heart
  2. Effects. Environ Health Perspect 2007; 115(11): 536-7.
  3. Stansfeld SA, Matheson MP. Noise pollution: nonauditory
  4. effects on health. Brit Med Bull 2003; 68:
  5. -57.
  6. Anger WK, Otto DA, Letz R. Symposium on
  7. computerized behavioral testing of humans in
  8. neurotoxicology research: Overview of the proceedings.
  9. Neurotoxicol Teratol 1996; 18(4): 347-50.
  10. Atmaca E, Peker I, Altin A. Industrial Noise and Its
  11. Effects on Humans. Pol J Environ Stud 2005; 14:
  12. -6.
  13. Daniel E. Noise and Hearing Loss: A Review. J School
  14. Health 2007; 77(5): 225-31.
  15. Smith AA. Review of the non auditory effects of noise
  16. on health. Work Stress 1991; 5: 49-62.
  17. Romero LM, Butler LK. Endocrinology of Stress. Int
  18. J Comp Psych 2007; 20: 89-95.
  19. Babisch W, Fromme H, Beyer A, Ising H. Increased
  20. catecholamine levels in urine in subjects exposed to road traffic noise the role of stress hormones in noise
  21. research. Environ Int 2001; 26: 475-81.
  22. Kakooei H, Zamanian Z, Ayattollahi SMT, Karimian
  23. M, Nasle Seraji G, Owji AA. The Effect of bright
  24. light on Physiological circadian rhythm and subjective
  25. alertness of shift work nurses in Iran. International
  26. Journal of Occupational Hygiene 2010; 16(4): 477-85.
  27. Zamanian Z, Kakooei H, Ayattollahi SMT. Effect of
  28. Bright Light on Shift Work Nurses in Hospitals. Pak J
  29. Biol Sci 2008; 13(9): 431-6.
  30. Waye K P, Bengtsson J, Rylander R, Hucklebridge
  31. F, Evans P, Clow A. Low frequency noise enhances
  32. cortisol among noise sensitive subjects during work
  33. performance. Life Sciences 2002; 70(7): 745-58.
  34. Melamed S, Bruhis S. The effects of chronic industrial
  35. noise exposure on urinary cortisol, fatigue and
  36. irritability- A controlled field experiment. Journal
  37. Occupational Environmental Medicine 1996; 38: 252-6.
  38. Bigert C, Bluhm G, Theorell T. Saliva cortisol – a new
  39. approach in noise research to study stress effects. Int J
  40. Hyg Environ. Health 2005; 208(3): 227-30.
  41. Kudielka BM, Kirschbaum C. Awakening cortisol
  42. responses are influenced by health status and
  43. awakening time but not by menstrual cycle phase.
  44. Psychoneuroendocrino 2003; 28(1): 35-47.
  45. Babisch W, Fromme H, Beyer A, Ising H. Increased
  46. catecholamine levels in urine in subjects exposed to
  47. road traffic noise the role of stress hormones in noise
  48. research. Environ Int 2001; 26(7-8): 475-81.
  49. Monsefi M, Bahoddini A, Nazemi S, Dehghani GA.
  50. Effects of Noise Exposure on the Volume of Adrenal
  51. Gland and Serum Levels of Cortisol in Rat. Iran J Med
  52. Sci 2006; 31: 5-8.
  53. Brandeberger G, Folle´nius M, Muzet A, Sime´oni M,
  54. Reinhardt B. Interactions between spontaneous and
  55. provoked cortisol secretory episodes in man. J Clin
  56. Endocr Metab 1984; 59(3): 406-11.
  57. Ising H, Braun C. Acute and chronic endocrine effects
  58. of noise: Review of the research conducted at the
  59. Institute for water, soil and air hygiene. Noise Health
  60. ; 2(7): 7-24.
  61. Golmohammadi R, Zamanparvar AR, Khalili A.
  62. Assessment of the relationship between noise and
  63. hearing loss in workers Isfahan Steel Rolling Workshop.
  64. Sci J Hamdan Univ Med Sci 2001; 8: 35-8. [Persian]
  65. Van Cauter E, Leproult R, Kupfer DJ. Effects of gender
  66. and age on the levels andcircadian rhythmicity of
  67. plasma cortisol. J Clin Endocrinol Metab 1996; 81:(7)
  68. -73.
  69. Roy M P. Patterns of cortisol reactivity to laboratory
  70. stress. Horm Behav 2004; 46(5): 618-27.
  71. Corbett BA, Mendoza SP, Baym CL, Bunge SA, Levine
  72. S. Examining cortisol rhythmicity and responsivity
  73. to stress in children with Tourette syndrome. Psycho
  74. neuroendocrino 2008; 33(6): 810-20.
  75. Elzinga BM, Bakker A, Bremner JD. Stress-induced
  76. cortisol elevations are associated with impaired
  77. delayed, but not immediate recall. Psychiat Res 2005;
  78. (3): 211-23.
  79. Prasher D. Is there evidence that environmental noise
  80. is immunotoxic? Noise Health 2009; 11(44): 151-5.
  81. Prasher D. Traffic noise increases stress by driving up
  82. cortisol. The Lancet 1998; 352: 1201.
  83. Ising H., Kruppa B. Health effects caused by noise:
  84. Evidence in the literature from the past 25 years. Noise
  85. Health 2004; 6(22): 5-13.
  86. Ball TM, Anderson D, Minto J, Halonen M. Cortisol
  87. circadian rhythms and stress responses in infants at risk
  88. of allergic disease. J Allergy Clin Immun 2006; 117(2):
  89. -11.
  90. Ising H, Babisch W, Kruppa B. Noise-induced
  91. endocrine effects and cardiovascular risk. Noise Health
  92. ; 1(4): 37-48.
  93. Ising H, Ising M. Chronic cortisol increases in the first
  94. half of the night caused by road traffic noise. Noise
  95. Health 2002; 4(16): 13-21.