Document Type : Review Articles

Authors

1 Department of Oral Medicine, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran

2 Department of Orthodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran

3 Research Center for Evidence Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

4 Dental and Periodontal Research Center, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran

5 Dental and Periodontal Research Center, Faculty of Dentistry,Tabriz University of Medical Sciences, Tabriz, Iran

Abstract

Background: New antimicrobial procedures are of significant importance to emerging species of bacteria and viruses. The objective of this systematic review study was to identify the efficacy, safety, and application of UV light in the disinfection of dental environments, instruments, and materials. Methods: In this systematic review article, the authors performed an electronic search of Google Scholar, Pubmed, and SCOPUS databases to retrieve related English language articles published between the years 1990 and 2020. At first, the selected articles were reviewed by screening their titles and abstracts and ultimately by full text. Results: 35 articles were considered relevant and included in this study. Fifteen studies were related to the antibacterial efficacy of UV radiation on various bacterial, fungal, and viral species. Two studies applied UV irradiation for the disinfection of titanium implants. Sixteen articles suggested the application of UV radiation for disinfection of dental impressions, toothbrushes, N95 masks, removable prostheses, acrylic resins, and surfaces. Furthermore, one study strongly suggested using eye protection appliances while working with UV radiation, and one study claimed that UVB radiation led to oral and skin cancer while this risk is higher for oral cancer. Conclusion: UV radiation with a specific dose and a duration effectively kills viruses, bacteria, and fungi for disinfection in dental procedures, which includes dental tools and materials such as toothbrushes, dental implants, impression materials, removable dentures, and dental environment. However, the principles of protection are emphasized to reduce its harmful effects on the eyes and skin.

Keywords

  1. Naik RG, Dodamani AS, Vishwakarma P, Khairnar MR, Jadhav HC, Deshmukh MA. Assessment of efficacy of ultraviolet chamber in disinfecting dental instruments. Asian Journal of Pharmaceutical and Health Sciences. 2016;6(4).
  2. Khaiboullina S, Uppal T, Dhabarde N, Subramanian VR, Verma SC. Inactivation of Human Coronavirus by Titania Nanoparticle Coatings and UVC Radiation: Throwing Light on SARS-CoV-2. Viruses. 2021; 13(1):19
  3. Aeran H, Sharma S,  Kumar V, Gupta N, Use of Clinical UV Chamber to Disinfect Dental Impressions: A Comparative Study, J Clin Diagn Res. 2015 Aug; 9(8): ZC67–ZC70.
  4. Kowalski, W. UVGI deactivation theory. In Ultraviolet Germicidal Irradiation Handbook; Springer: New York, NY, USA, 2009; pp. 17–50.
  5. Casini B, Tuvo B, Cristina ML, Spagnolo AM, Totaro M, Baggiani A, Privitera GP. Evaluation of an Ultraviolet C (UVC) Light-Emitting Device for Disinfection of High Touch Surfaces in Hospital Critical Areas. International Journal of Environmental Research and Public Health. 2019; 16(19):3572
  6. D'Orazio J, Jarrett S, Amaro-Ortiz A, Scott T. UV Radiation and the Skin. International Journal of Molecular Sciences. 2013; 14(6):12222-12248
  7. Dai T, Vrahas MS, Murray CK ,Ultraviolet C irradiation: an alternative antimicrobial approach to localized infections?, Expert Review of Anti-infective Therapy , 2012,10(2): 185-195
  8. Takada A, Matsushita K, Horioka S, Furuichi Y, Sumi Y. Bactericidal effects of 310 nm ultraviolet light-emitting diode irradiation on oral bacteria. BMC Oral Health. 2017;17(1):96.
  9. Ogawa T. Ultraviolet photofunctionalization of titanium implants. Int J Oral Maxillofac Implants. 2014 ,;29(1):e95-102.
  10. Tseng CH.CH ,  Li SH, Inactivation of Virus-Containing Aerosols by Ultraviolet Germicidal Irradiation, Aerosol Science and Technology ,2005,39(12): 1136-1142
  11. Tenkumo T, Ishiyama K, Prymak O, Nakamura K, Shirato M, Ogawa T, Miyashita M, Takahashi M, Epple M, Kanno T, Sasaki K. Bactericidal activity and recovery effect of hydroxyl radicals generated by ultraviolet irradiation and silver ion application on an infected titanium surface. Sci Rep. 2020 May 22;10(1):8553.
  12. Ishida H, Nahara Y, Tamamoto M, Hamada T. The fungicidal effect of ultraviolet light on impression materials. +J Prosthet Dent. 1991 Apr;65(4):532-5.
  13. Binns R,  Li  W,  D Wu  CH, Campbell  S,  Knoernschild   K,  Yang  B , Effect of Ultraviolet Radiation on Candida albicans Biofilm on Poly(methylmethacrylate) Resin , J Prosthodont , . 2020 Oct;29(8):686-692.
  14. Lemons   R,  McClelland   T.L,  Martin Jr  S.B,  Lindsley  W.G,  Green   B.J, Inactivation of the multi-drug resistant pathogen Candida auris using ultraviolet germicidal irradiation (UVGI) , J Hosp Infect , . 2020 Apr 10;S0195-6701(20)30186-9.
  15. Buonanno M, Welch D, Shuryak I, Brenner DJ. Far-UVC light (222 nm) efficiently and safely inactivates airborne human coronaviruses. Sci Rep. 2020;10(1):10285.
  16. Gerchman Y, Mamane H, Friedman N, Mandelboim M. UV-LED disinfection of Coronavirus: Wavelength effect. J Photochem Photobiol B. 2020 Nov;212:112044.
  17. DruceD, Jardine D,  Locarnini S.A,  Birch C.J, Susceptibility of HIV to inactivation by disinfectants and ultraviolet light, J Hosp Infect, 1995 Jul;30(3):167-80.
  18. He  J,  Moriya Y,  Oketa T,  Sasabe SH, Nishida H, Chen L, Zhu SH,  Zhang D, Omori H, Cao G, [Inactivation mechanism of microorganisms by the synergy of silver and light irradiation, and the application in household electrical appliances], Sheng Wu Gong Cheng Xue Bao , . 2008 Jun;24(6):1091-7.
  19. Dorigatti de Avila  E, P Lima  B,  Sekiya  T, Torii  Y,  Ogawa  T Shi   W Lux   R , Effect of UV-photofunctionalization on oral bacterial attachment and biofilm formation to titanium implant material , Biomaterials , . 2015 Oct;67:84-92.
  20. Areid N, Soderling E, Tanner J, Kangasniemi I, Narhi TO. Early Biofilm Formation on UV Light Activated Nanoporous TiO2 Surfaces In Vivo. Int J Biomater. 2018;2018:7275617.
  21. Risović D, Maver-Bišćanin M, Mravak-Stipetić M, Bukovski S, Bišćanin A. Quantitative investigation of efficiency of ultraviolet and visible light in eradication of Candida albicans in vitro. Photomedicine and laser surgery. 2014;32(4):232-9.
  22. Heilingloh CS, Aufderhorst UW, Schipper L, Dittmer U, Witzke O, Yang D, Zheng X, Sutter K, Trilling M, Alt M, Steinmann E, Krawczyk A. Susceptibility of SARS-CoV-2 to UV irradiation., Am J Infect Control. 2020 Oct;48(10):1273-1275.
  23. KrieselD,  Pisani P.L,  McKeough M.B,  Baringer J.R,  Spruance S.L , Correlation between detection of herpes simplex virus in oral secretions by PCR and susceptibility to experimental UV radiation-induced herpes labialis, J Clin Microbiol , . 1994 Dec;32(12):3088-90.
  24. Taylor GJ, Bannister GC, Leeming JP. Wound disinfection with ultraviolet radiation. J Hosp Infect. 1995 Jun;30(2):85-93.
  25. Labrie D, Moe J, Price RB, Young ME, Felix CM. Evaluation of ocular hazards from 4 types of curing lights. J Can Dent Assoc. 2011;77(116):b116.
  26. Agrawal A, Shindell E, Jordan F, Baeva L, Pfefer J, Godar DE.UV radiation increases carcinogenic risks for oral tissues compared to skin. Photochem Photobiol. 2013 Sep-Oct;89(5):1193-8.
  27. Ozog  D,  SextonZ, Narla  SH,  Pretto-Kernahan  C.DMirabelli  C,  Lim   H,  Hamzavi  I.H Tibbetts   R.J,  Mi   Q, The effect of ultraviolet C radiation against different N95 respirators inoculated with SARS-CoV-2, Int J Infect Dis , . 2020 Nov;100:224-229.
  28. Liao L, Xiao W Zhao M, Yu X, Wang H, Wang Q, Chu S, Cui Y, Can N95 Respirators Be Reused after Disinfection? How Many Times?, ACS Nano 2020, 14(5): 6348–6356,
  29. Byrns G, Barham B,  Yang L, Webster K, Rutherford G,  Steiner G, Petras D, Scannell M, The uses and limitations of a hand-held germicidal ultraviolet wand for surface disinfection, J Occup Environ Hyg. 2017; 14(10): 749–757.Gujjari SK,
  30. Vinaya Kumar G, Wadhwani A, Hajira N. Effect of UV disinfection on dimensional stability and infection control of elastomeric impression materials. CODS J Dent 2015;7:60-63
  31. Zhang W, Mao H, Zhou G, Effect of ultraviolet radiation combined with immersion      disinfection of silicone impressions infected with hepatitis B virus and HIV, Biomedical Research ,2017,28(14)
  32. Yildirim-BicerZ,  Peker  I , Akca  G,  Celik   I, In vitro antifungal evaluation of seven different disinfectants on acrylic resins, Biomed Res Int , . 2014;2014:519098
  33. AbdulkareemM, EFFECTIVENESS OF ULTRAVIOLET LIGHT ON THE DISINFECTION OF COMPLETE DENTURES,2020,
  34. Tomar P Hongal SSaxena V Jain  M Rana  K Ganavadiya  R, Evaluating sanitization of toothbrushes using ultra violet rays and 0.2% chlorhexidine solution: A comparative clinical study, J Basic Clin Pharm , 2014 Dec;6(1):12-8.
  35. Gujjari AK, Patel PV, Shubhashini PV. Comparative evaluation of ultraviolet and microwave sanitization techniques for toothbrush decontamination. J Int Soc Prev Community Dent. 2011 Jan;1(1):20-6.
  36. Bélanger-Giguère K, Giguère S, Bélanger M. Disinfection of toothbrushes contaminated with Streptococcus mutans. Am J Dent. 2011 Jun;24(3):155-8.
  37. Peker I, Akca G, Sarikir C, Alkurt MT, Celik I. Effectiveness of alternative methods for toothbrush disinfection: an in vitro study. 2014;2014:726190.
  38. Shin A.R , NamH, Antimicrobial effects of various methods for the disinfection of contaminated toothbrushes, Biomedical Research, 2018,29(13)
  39. Berger JR, Drukartz MJ, Tenenbaum MD. The efficacy of two UV toothbrush sanitization devices. A pilot study. 6N Y State Dent J. 2008 Jan;74(1):50-2.
  40. Metzger Z, Better H, Abramovitz I, Immediate root canal disinfection with ultraviolet light: an ex vivo Feasibility study, Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;104:425-33
  41. Yoshino F, Yoshida A. Effects of blue-light irradiation during dental treatment. Jpn Dent Sci Rev. 2018;54(4):160-8.
  42. Bruzell RollM.B,  Jacobsen N,  Hensten-Pettersen A , Health hazards associated with curing light in the dental clinic, Clin Oral Investig , . 2004 Sep;8(3):113-7.