Document Type : Original Article


1 Thoracic and Vascular Surgery Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

2 Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran

3 Non-communicable Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

4 Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran



Background: Knowledge and awareness of disease transmission modes and basic hygiene principles during a public health crisis are crucial for developing effective control measures. The researchers aimed to evaluate Iranians’ knowledge, attitude, and practice (KAP) throughout the coronavirus disease 2019 (COVID-19) pandemic to detect related sociodemographic variables.
Methods: This cross-sectional, web-based survey was conducted from the 2nd - 8th March 2020 among the general population of Iran above 15 years of age. A 76-item self-designed questionnaire regarding KAP towards COVID-19 was used, and the participants’ demographic characteristics and sources of information were collected. The Snowball sampling method was applied for data collection, and responses were scored based on the Likert scale. Simple and multiple linear regression was performed using SPSS version 26. The statistical significance level was P<0.05.
Results: Among 8591 participants, the overall achieved knowledge, attitude, and practice score regarding COVID- 19 characteristics were 90%, 90%, and 89%. Also, an overall score of 85% was achieved regarding the knowledge of the transmission mode and high-risk groups for COVID-19. There was a significant association between female gender, higher age, and higher education with knowledge, attitude, and practice. Male gender, being single, and lower education levels were associated with lower scores in knowledge and practice (P<0.001) and poorer attitudes towards COVID-19 (P<0.001, 0.002, and <0.001, respectively).
Conclusion: During its outbreak, the Iranian population demonstrated decent knowledge, appropriate practice, and a positive attitude towards COVID-19. Furthermore, health education programs, mainly targeting lower-knowledge individuals regarding COVID-19, are essential for encouraging a positive attitude and maintaining safe practices. Hopefully, by increasing knowledge via public health policymakers and the cooperation of the Iranian authorities and the general population, optimistic control and elimination of the disease can be anticipated.


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